Global cirrhosis prevalence trends and attributable risk factors-an ecological study using data from 1990-2019Article Published on 2022-12-012023-06-12 Journal: Liver international : official journal of the Inte [Category] B형 간염, [키워드] Hepatitis Intervention Liver disease prediction time series. [DOI] 10.1111/liv.15421 PMC 바로가기
Diversity of the nucleic acid forms of circulating HBV in chronically infected patients and its impact on viral cycleMulticenter Study Published on 2022-12-012023-06-12 Journal: Hepatology international [Category] B형 간염, [키워드] alternative splicing chronic hepatitis chronic infection HBV HBV pregenomic RNA Liver disease Viral circulating forms Viral cycle Viral genome diversity Viral hepatitis. [DOI] 10.1007/s12072-022-10389-6 PMC 바로가기 [Article Type] Multicenter Study
Seroprevalence and clinical outcome of hepatitis D infection in QatarArticle Published on 2022-11-302023-06-11 Journal: Eastern Mediterranean health journal = La revue de santé de la [Category] B형 간염, [키워드] Co-infection hepatitis B Hepatitis D Liver disease Qatar surface antigen viraemia. [DOI] 10.26719/emhj.22.081 PMC 바로가기
Randomized, double-blind, placebo-controlled, crossover trial of oral doxycycline for epistaxis in hereditary hemorrhagic telangiectasiaArticle Published on 2022-11-072022-11-16 Journal: Orphanet Journal of Rare Diseases [Category] 유전자 메커니즘, [키워드] analysis Angiogenesis assigned Biomarkers bleeding Blood center double-blind doxycycline Effectiveness ENG Epistaxis Frequency heart failure help hemorrhage Hemorrhagic Hereditary Hereditary hemorrhagic telangiectasia Hereditary hemorrhagic telangiectasia. HHT IL-6 Inflammatory intravenous limitations Liver disease malformation marker mechanism Michael morbidity no significant difference not significantly different observation pathway Patient Placebo placebo-controlled provided Quality of life Randomized controlled trial Randomly RBC recruited Registered Registration secondary significantly higher stroke telangiectasia therapy Toronto Treatment treatment period Trial VEGF [DOI] 10.1186/s13023-022-02539-8 PMC 바로가기
New-onset and relapsed liver diseases following COVID-19 vaccination: a systematic reviewArticle Published on 2022-10-132022-11-15 Journal: BMC Gastroenterology [Category] 진단, [키워드] article Autoimmune hepatitis benefit cellular CINAHL complications COVID-19 COVID-19 vaccination COVID-19 vaccines disease English language Evidence hepatic hepatic failure Hepatic porphyria Hepatitis hepatomegaly incidence include indicated item jaundice liver Liver disease liver enzyme Liver injury Meta Most patient Nature occur occurred offered Other pathology post-COVID-19 vaccination Protective raised rejection reported Reporting review Safety SARS-CoV-2 searched side Side effect systematic review therapy thrombosis treated vaccination vaccine. worldwide pandemic [DOI] 10.1186/s12876-022-02507-3 PMC 바로가기
Sex differences in determinants of COVID-19 severe outcomes – findings from the National COVID Cohort Collaborative (N3C)Article Published on 2022-10-122022-11-15 Journal: BMC Infectious Diseases [Category] 바이오마커, [키워드] absolute lymphocyte absolute neutrophil adjusted adjusted odds ratio Admission age Analysis association averaged Biomarker Biomarkers both sexes CCI Charlson Comorbidity Index comorbid condition Comorbidities Comorbidity components COVID COVID-19 COVID-19 severity CRP death death rate defined determinant disease Elevation examined ferritin Health highlight hospital Hospitalized IMV Inflammation inflammatory biomarkers Invasive mechanical ventilation lab value Liver disease Logistic regression LOS lymphocytopenia magnitude male medication men men and women moderate to severe Mortality Myocardial infarction N-terminal neutrophil outcome Patient peptide Platelet Platelets predictor previous study Primary outcome procalcitonin Protein remained renal Research retrospective cohort risk risk factor risk of death secondary outcome Sex Sex difference sex differences. significantly solid tumor with COVID-19 women [DOI] 10.1186/s12879-022-07776-7 PMC 바로가기
Association between immunosuppressants and poor antibody responses to SARS-CoV-2 vaccines in patients with autoimmune liver diseasesArticle Published on 2022-10-052022-11-15 Journal: Frontiers in Immunology [Category] COVID19(2023년), SARS, 진단, 치료기술, [키워드] 95% CI 95% confidence interval acute respiratory syndrome addition adjusted odds ratio AEs All adverse event antibody Antibody Response Autoimmune autoimmune liver diseases B cell response BBIBP-CorV Chongqing comparable conducted confounders Control CoronaVac coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 vaccination flow cytometry groups HCs healthy healthy control higher risk immunogenicity Immunosuppressant immunosuppressants immunosuppressive inactivated incidence independent risk factor liver Liver disease memory B cell Mild NAb NAbs participant Patient patients physician Population Probability prospective observational study RBD reduced response Safe Safety SARS-CoV-2 vaccination SARS-CoV-2 vaccine SARS-CoV-2-specific B cell second severe acute respiratory syndrome coronavirus 2 significantly significantly lower Spike protein tested the receptor-binding domain the SARS-CoV-2 therapy university vaccination Vaccine vaccine. Vaccines were recorded [DOI] 10.3389/fimmu.2022.988004 PMC 바로가기
COVID-19-associated liver injury: Clinical characteristics, pathophysiological mechanisms and treatment managementReview article Published on 2022-10-012022-10-05 Journal: Biomedicine & pharmacotherapy = Biomédecine & phar [Category] COVID19(2023년), SARS, 임상, 진단, 치료기술, 치료법, 치료제, [키워드] acute respiratory syndrome addition aggravate Asymptomatic caused Characteristics chronic liver disease cirrhosis clinical clinical manifestation Complication Coronavirus disease 2019 Coronavirus-2 COVID-19 COVID-19 patient Critical death disease dysfunction Epidemic extrapulmonary organs Factors hepatic function Hepatocellular carcinoma hypoxia immune increased risk infection with SARS-CoV-2 inflammatory factor storms Injury liver Liver damage Liver disease liver enzyme Liver function Liver injury liver transplant Liver transplantation management mechanism nonalcoholic fatty liver pathophysiological mechanism Patient patients prevalent public health reperfusion Respiratory disease risk SARS-CoV-2 severe disease Stress Treatment Vaccine [DOI] 10.1016/j.biopha.2022.113568 [Article Type] Review article
High prevalence of chronic viral hepatitis B and C in Minnesota Somalis contributes to rising hepatocellular carcinoma incidenceArticle Published on 2022-09-212023-06-12 Journal: World journal of gastroenterology [Category] B형 간염, [키워드] African Community engagement immigrant health Liver disease Viral hepatitis. [DOI] 10.3748/wjg.v28.i35.5217 PMC 바로가기
A home-based, multidisciplinary liver optimisation programme for the first 28 days after an admission for acute-on-chronic liver failure (LivR well): a study protocol for a randomised controlled trialArticle Published on 2022-09-052022-10-05 Journal: Trials [Category] 임상, [키워드] 1:1 28-day mortality addition Admission Admissions Analysis Appendix 1 benefit Care changes in chronic chronic condition chronic disease chronic liver disease cirrhosis clinical Clinical improvement Clinicians Cohort conducted COVID-19 COVID-19 pandemic criteria disease evaluated exploratory subgroup analysis feasibility generalisability generate global healthcare Health Health Service health team healthcare Healthcare systems heart failure hospitalisation implementation implication include Interdisciplinary health team. interim analysis Intervention intervention arm liver Liver disease Melbourne, Australia Mortality mortality risk New outcome participant Patient performed Prevalence Primary outcome Quality of life randomisation randomised randomised controlled trial RCT readmission recruit recruited recruitment reduced reducing Registered Registration registry required resource rising robust Safe secondary severity small sample size social work Study protocol suggested Treatment Trial well WHO [DOI] 10.1186/s13063-022-06679-x PMC 바로가기 [Article Type] Article